[Final] Lecture 36 12/8; Review

Review sheet on blackboard! Contains the main concepts that will be on the test.

(6:00) Complete linkage.

(17:15) Three factor cross mapping

• (30:10) Mapping distance

(34:40) Chi squared analysis

(38:30) Meiosis

(39:05) Lyon Hypothesis


This is the review he posted on blackboard.

BIOL 3210
Final Exam Review Sheet

This review sheet will give you potential topics for problems/ short answer/ essay questions. All of the material covered during the semester is subject to multiple choice questions.

1.) How to perform monohybrid and dihybrid crosses
2.) How to perform trihybrid crosses using the forked-line or branch diagram
3.) How to perform chi-square analysis and determine whether or not to reject or fail to reject a hypothesis
4.) The application of the binomial theorem in order to calculate the probability of an event happening
5.) The various unusual patterns of inheritance and how those patterns affect the passage of genes from one generation to the next
6.) How to perform linkage mapping, calculate mapping units between genes, calculate interference and coefficient of confidence
7.) Being able to draw all four structures of the bases and the structures of deoxyribose and ribose
8.) Understanding the experiments of Griffith. How were they performed and what were the results
9.) Understanding the experiments of Avery, MacLeod and McCarty. How would the results have been different if RNA was the genetic material and not DNA.
10.) Understanding the Hershey-Chase experiments. How were they performed and what were the results. How would the results have been different if RNA was the genetic material and not DNA?
11.) Describe the experiments that showed that Hfr strains could be used to determine the relative order of genes on the prokaryotic chromosomes
12.) Understand how the fluctuation test was performed. What were the two hypothesis that were being tested? What were the results that were obtained and how would the results have been different if the other hypothesis was correct?
13.) Use of pedigree analysis to follow a trait through generations within a family. Using this technique to understand the mode of inheritance as well as to determine the genotype or potential genotypes for individuals in a family
14.) Describe the Linderberg –Zinder experiment and the nature of transduction
15.) Understand the evidence that Watson and Crick used in order to describe the double helical nature of DNA
16.) Be able to describe the experiment that first showed that genetic recombination required physical interaction between cells
17.) Be able to describe the complete life cycle of a bacteriaphage
18.) Understand how gene duplication functions to allow for the formation of new genes
19.) Know the sequence elements found in the eukaryotic promoter and how their importance was established
20.) Be able to describe the nature of the regulation of gene expression for the lac operon in the presence of: (a) lactose; (b) no sugar; (c) lactose and glucose
21.) Be able to describe the nature of the gene regulation for the GAL genes in the presence of: (a) galactose; (b) no sugar; (c) galacotse and glucose
22.) Be able to describe the nature of the regulation of the trp operon in the presence and absence of tryptophan
23.) Understand how compounds are tested to determine if they are in fact carcinogens
24.) Know the levels at which eukaryotic gene regulation can take place: be able to give an example for each level
25.) Be able to describe the first two levels of chromosome packing and the key pieces of evidence that supported these two models
26.) Be able to describe tumor suppressor genes and oncogenes. Be able to give an example of each
27.) Be able to describe the process of nucleotide excision repair
28.) Describe the lyon hypothesis and the data that supports the lyon hypothesis
29.) Be able to describe the differences between maternal effect and organelle heredity
30.) Be able to describe how a monosomy or trisomy arises and give an example of a disease caused by each